Lipid biomarker-based verification of TB infection in mother’s and daughter’s mummified human remains (Vác Mummy Collection, 18th century, CE, Hungary)

The perpetual burden of tuberculosis (TB) keeps drawing the focus research on this disease. Among other risk factors (e.g., poor living conditions, malnutrition, smoking, HIV infection, etc.), being in close contact with a TB infected person requires special attention. For better understanding disease, paleopathological investigations concerning have been carried out various techniques for long time; nevertheless, analysis incidence among family members is hardly possible past populations. An exceptional group naturally mummified individuals, collection Vác mummies (Hungary, 18th century CE), known about large rate, which has revealed by aDNA analysis. Besides high rate another interesting aspect that some cases, connections could be reconstructed. In paper, we present mycocerosic acid profiles gained HPLC-HESI-MS measurements two mummies, who were mother and daughter according to personal records. Earlier metagenomic already mixed M. infection same bacterial strains both individuals; moreover, recorded cases.